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FDA Approves Many Drugs that Predictably Increase Heart and Stroke Risk
The agency charged to protect patients from dangerous drug side effects needs to be far more vigilant when it comes to medications that affect blood pressure. Robert P. Blankfield, MD, MS, a clinical professor of family medicine, issues this call to the U.S. Food and Drug Administration (FDA) in an...
Dr. Neal Meropol Honored as American Society of Clinical Oncology Fellow
The American Society of Clinical Oncology (ASCO) will honor Neal J. Meropol, MD, as a Fellow during the May 31 Opening Session of the 2014 ASCO Annual Meeting in Chicago. He will be one of 12 exceptional members to earn the designation of Fellow as a result of their extraordinary volunteer service, ...
Physician Practice Facilitation Ensures Key Medical Care Reaches Children
Leona Cuttler, MD, knew in her core that the simple act of adding an outside eye could dramatically improve pediatric care. Today, a study of more than 16,000 patient visits published online in the journal Pediatrics proves Cuttler’s thesis correct. The lead investigator on the research project, Cu...
Investigators Discover How Key Protein Enhances Memory and Learning
ºÚÁϳԹÏÍø researchers have discovered that a protein previously implicated in disease plays such a positive role in learning and memory that it may someday contribute to cures of cognitive impairments. The findings regarding the potential virtues of fatty acid binding protein 5 (FABP5) — ...
$2.3M Study to Examine How Neighborhoods Influence Child Maltreatment Rates
The Eunice Kennedy Shriver National Institute of Child Health and Human Development awarded a $2.3 million grant to three ºÚÁϳԹÏÍø schools and colleges. The team of researchers will study child maltreatment in 20 Cleveland neighborhoods, examining the role that neighborhood co...
Study Shows Aspirin Can Reduce Colorectal Cancer Risks for Those with Specific Gene
CLEVELAND/BOSTON – April 23, 2014 –The humble aspirin may have just added another beneficial effect beyond its ability to ameliorate headaches and reduce the risk of heart attacks: lowering colon cancer risk among people with high levels of a specific type of gene. The extraordinary finding comes ...
Heart Attack Gene, MRP-14, Triggers Blood Clot Formation
Right now, options are limited for preventing heart attacks. However, the day may come when treatments target the heart attack gene, myeloid related protein-14 (MRP-14, also known as S100A9) and defang its ability to produce heart attack-inducing blood clots, a process referred to as thrombosis. Sc...
Nature Immunology Study Finds Novel Population of Neutrophils
ºÚÁϳԹÏÍø researchers have discovered a novel population of neutrophils, which are the body’s infection control workhorses. These cells have an enhanced microbial killing ability and are thereby better able to control infection. Neutrophils, the body’s most abundant type of wh...
Microorganism Shows Promise in Inhibiting Thrush
Scientists at ºÚÁϳԹÏÍø School of Medicine and University Hospitals (UH) Case Medical Center have discovered how the beneficial fungal yeast, Pichia, holds at bay a harmful fungal yeast, Candida. Candida is the culprit in oral candidiasis, a painful mouth infection known as thrush. The ho...
Case Comprehensive Cancer Center Researchers Discover Pathway of Protein that Helps Cancer Cells Survive
A team of researchers from ºÚÁϳԹÏÍø School of Medicine has discovered how the cancer-related protein Bcl-2 signals cancer cells to live longer. The breakthrough emerged when the scientists discovered that Bcl-2 alters the level of calcium ions in lymphoma and leukemia cells that are res...