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Cuyahoga County High School Students Smoking at the Same Rate as Adults
Cuyahoga County high school students are smoking tobacco products at the same rate as adults in the county, according to new data from the Prevention Research Center for Healthy Neighborhoods (PRCHN) at ϳԹ. In 2013, more than 22 percent, or one in five high school studen...
International Research Team Discovers Genetic Dysfunction Connected to Hydrocephalus
The mysterious condition once known as “water on the brain” became just a bit less murky this week thanks to a global research group led in part by a ϳԹ researcher. Professor Anthony Wynshaw-Boris, MD, PhD, is the co-principal investigator on a study that illustrates how the domino...
Bacteria Hijack Plentiful Iron Supply Source to Flourish
In an era of increasing concern about the prevalence of antibiotic-resistant illness, ϳԹ researchers have identified a promising new pathway to disabling disease: blocking bacteria’s access to iron in the body. The scientists showed how bacterial siderophore, a small molecule, cap...
ϳԹ Researchers and Collaborators Receive $12.6 Million NIH Grant to Study Genetics of Alzheimer’s Disease
Researchers from ϳԹ School of Medicine are part of a five-university collaboration receiving a $12.6 million, four-year grant from the National Institute on Aging (NIA), part of the National Institutes of Health (NIH), to identify rare genetic variants that may either pr...
ϳԹ, University Hospitals Announce Collaborative Fundraising Initiative for Adolescent and Young Adult Cancer
Leaders from ϳԹ and University Hospitals this evening announced a new collaborative fundraising effort focused on Adolescent and Young Adult (AYA) cancer. The news came as Char and Chuck Fowler announced their third major philanthropic commitment aimed at defeating the d...
Synthetic Triterpenoids Show Promise in Preventing Colitis-Associated Colon Cancer
Researchers from ϳԹ and Dartmouth universities have shown that a class of small antioxidant molecules carries enormous promise for suppressing colon cancer associated with colitis. These findings, published in an early June edition of the Journal of Clinical Investigation, offer ho...
Long Non-coding RNAs Can Encode Proteins After All
ϳԹ School of Medicine scientists have made an extraordinary double discovery. First, they have identified thousands of novel long non-coding ribonucleic acid (lncRNA) transcripts. Second, they have learned that some of them defy conventional wisdom regarding lncRNA transcripts, bec...
Family of Proteins Plays Key Role in Cellular Pump Dynamics
ϳԹ scientists have discovered how a family of proteins — cation diffusion facilitators (CDFs) — regulates an important cellular cycle where a cell’s energy generated is converted to necessary cellular functions. The finding has the potential to inform future research aim...
Cancer Drug Boosts Levels of Vascular-Protective Gene, KLF2
ϳԹ researchers have discovered that an existing drug used to help cancer patients has the potential to protect thousands of others from the often-deadly impact of vascular clots. In 2008, the Food and Drug Administration approved bortezomib (Velcade) to treat multiple m...
Stem Cells Hold Keys to Body’s Plan
ϳԹ researchers have discovered landmarks within pluripotent stem cells that guide how they develop to serve different purposes within the body. This breakthrough offers promise that scientists eventually will be able to direct stem cells in ways that prevent disease or repair damag...