ºÚÁϳԹÏÍø

A surgical sedative may hold the key to reversing the devastating symptoms of a neurodevelopmental disorder found almost exclusively in females. Ketamine, used primarily for operative procedures, has shown such promise in mouse models that ºÚÁϳԹÏÍø and Cleveland Clinic researchers soon w...

The concept was simple: If two compounds each individually show promise in preventing colon cancer, surely it’s worth trying the two together to see if even greater impact is possible. In this instance, ºÚÁϳԹÏÍø cancer researcher Li Li, MD, PhD, could not have been more prescient. Not ...

Half a century ago, a concentrated global effort nearly wiped a disfiguring tropical disease from the face of the earth. Now, says ºÚÁϳԹÏÍø’s James W. Kazura, MD, it’s time to complete the work. In a perspective column in the Feb.19 New England Journal of Medicine, Kazura responded to a...

ºÚÁϳԹÏÍø researchers are part of an international team that has discovered that a common herpes drug reduces HIV-1 levels — even when patients do not have herpes. Published online in Clinical Infectious Diseases, the finding rebuts earlier scientific assumptions that Valacyclovir (brand...

ºÚÁϳԹÏÍø scientists have discovered that speed matters when it comes to how messenger RNA (mRNA) deciphers critical information within the genetic code — the complex chain of instructions critical to sustaining life. The investigators’ findings, which appear in the March 12 journal Cell,...

A researcher at ºÚÁϳԹÏÍø School of Medicine has been awarded $3.9 million to determine if the combination of the human immunodeficiency virus (HIV) and drug abuse is a double kick in the gut, leading to organ damage throughout the body. Alan D. Levine, PhD, a professor of med...

ºÚÁϳԹÏÍø’s chemical compound aimed at restoring spinal cord function may have an additional purpose: stopping potentially fatal arrhythmias after heart attack. ºÚÁϳԹÏÍø neurosciences professor Jerry Silver, PhD, long has believed that lessons learned over decades from spina...

ºÚÁϳԹÏÍø scientists have taken a huge leap toward identifying root causes of psoriasis, an inflammatory skin condition affecting 125 million people around the world. Of the roughly 50,000 proteins in the human body, researchers have zeroed in on four that appear most likely to contribute...

ºÚÁϳԹÏÍø and University Hospitals (UH) Case Medical Center researchers and physicians have discovered that the molecule known as coenzyme A plays a key role in cell metabolism by regulating the actions of nitric oxide. Cell metabolism is the ongoing process of chemical transformations wi...

Case Comprehensive Cancer Center researchers have identified new gene mutations unique to colon cancers in African Americans – the population with the highest incidence and death rates of any group for this disease. This discovery – namely, that colorectal cancers appear different on a molecular l...