ºÚÁϳԹÏÍø

Bottom Line: Researchers discovered three novel genetic mutations associated with Fuchs endothelial corneal dystrophy, the most common corneal disorder requiring transplantation. Journal in Which the Study was Published: Nature Communications Author: Sudha K. Iyengar, PhD, Professor of Epidemiolog...

A light-sensing pigment found in everything from bacteria to vertebrates can be biochemically manipulated to reset itself, an important therapeutic advantage, according to new research out of ºÚÁϳԹÏÍø School of Medicine. In a study just released from the Proceedings of the Nat...

Two biophysicists from ºÚÁϳԹÏÍø School of Medicine have used supercomputers to show how cell membranes control the shape, and consequently the function, of a major cancer-causing protein. The protein, a small enzyme called K-Ras, is attached to cell membranes where it senses s...

Researchers led by Julian E. Stelzer, PhD, associate professor in the department of physiology and biophysics at ºÚÁϳԹÏÍø School of Medicine, have found a new target for drug developers seeking straightforward ways to improve cardiac output in heart failure patients. In a rece...

ºÚÁϳԹÏÍø School of Medicine and the Case Comprehensive Cancer Center have been named to a new colorectal cancer dream team that was announced today at the annual meeting of the American Association for Cancer Research in Washington, D.C. The dream team comprises scientists, cl...

ºÚÁϳԹÏÍø and Q2 Pharma Ltd., an Israeli biopharmaceutical company, have signed a two-year option to license small molecule, antivirulence technology to potentially treat bacterial infections such as methicillin-resistant staphylococcus aureus (MRSA), the first known scientific...

Researchers at ºÚÁϳԹÏÍø School of Medicine have successfully grown stem cells from children with a devastating neurological disease to help explain how different genetic backgrounds can cause common symptoms. The work sheds light on how certain brain disorders develop, and pro...

A massive new study involving blood samples from over 30,000 individuals has identified 13 new genetic risk factors for glioma, the most common type of malignant brain tumor in adults. The study, published in Nature Genetics, reveals specific differences in a person’s DNA that increase susceptibilit...

A ºÚÁϳԹÏÍø School of Medicine and MetroHealth System researcher, along with Cleveland Clinic’s director of metabolic research, have received federal funding to determine if childhood obesity can be prevented before women become pregnant. The first-ever Cleveland-based study w...

One of the biggest challenges in studying Down syndrome is finding the right research model. Animals and established cell lines are limited in their ability to mimic human disease, and results don’t always translate to patient populations. Stem cells hold enormous potential as research tools that ca...