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ºÚÁϳԹÏÍø Researcher Awarded Over $4.7 Million to Develop Drug-Delivery Nanotechnology
Nicole F. Steinmetz, PhD, George J. Picha Professor in Biomaterials, member of the Case Comprehensive Cancer Center, and Director of the Center for Bio-Nanotechnology at ºÚÁϳԹÏÍø School of Medicine, has received two major grants from the National Institutes of Health to develop microscop...
Injectable Plant-based Nanoparticles Delay Tumor Progression
Researchers from ºÚÁϳԹÏÍø School of Medicine in collaboration with researchers from Dartmouth Geisel School of Medicine and RWTH Aachen University (Germany) have adapted virus particles—that normally infect potatoes—to serve as cancer drug delivery devices for mice. But in a r...
High Fat Diet Reduces Gut Bacteria, Crohn’s Disease Symptoms
Researchers at ºÚÁϳԹÏÍø School of Medicine have shown a high fat diet may lead to specific changes in gut bacteria that could fight harmful inflammation—a major discovery for patients suffering from Crohn’s disease. Crohn’s disease, a type of inflammatory bowel syndrome, cause...
Single Fungus Amplifies Crohn’s Disease Symptoms
Bottom Line: A microscopic fungus called Candida tropicalis triggered gut inflammation and exacerbated symptoms of Crohn’s disease, in a recent study conducted at ºÚÁϳԹÏÍø School of Medicine. Meeting Where the Study was Presented: Digestive Disease Week® May 5-9, 2017 at McCo...
Researchers Call for Paradigm Shift in Type 2 Diabetes Treatment
Heart disease is a leading cause of death worldwide and exacerbated by type 2 diabetes, yet diabetes treatment regimens tend to focus primarily on blood sugar maintenance. This common approach to type 2 diabetes management can leave patients at risk for heart attack and stroke. But results from four...
ºÚÁϳԹÏÍø Receives $6 Million to Study Barrett’s Esophagus
The National Cancer Institute recently awarded a $6 million grant to the Case Comprehensive Cancer Center and ºÚÁϳԹÏÍø School of Medicine to continue research on Barrett’s Esophagus, a potentially fatal condition caused by long-term acid reflux. Reflux can cause tissue lining ...
Small Molecule Prevents Blood Clots without Increasing Bleeding Risk
It may be possible to disrupt harmful blood clots in people at risk for heart attack or stroke without increasing their risk of bleeding, according to a new study published in Nature Communications. The new research out of University Hospitals (UH) Cleveland Medical Center, ºÚÁϳԹÏÍø Uni...
Early MRI May Lower Costs for Prostate Cancer Treatment
A diagnostic MRI followed by one of three MRI-guided biopsy strategies is a cost-effective method to detect prostate cancer, according to a new study out of ºÚÁϳԹÏÍø School of Medicine and University Hospitals Cleveland Medical Center. Researchers compared MR-guided approaches...
Prototype Drug Uses Novel Mechanism to treat lung cancers
Bottom Line: Lung cancer tumors were prevented in mice by a novel small molecule that directly activates a tumor suppressor protein. Journal in Which the Study was Published: The Journal of Clinical Investigation Author: Goutham Narla, MD, PhD, Pardee-Gerstacker Professor in Cancer Research, Assoc...
ºÚÁϳԹÏ꿉۪s Martin Basch receives prestigious Hartwell Foundation Award for research on congenital deafness
In the United States, almost three of every 1,000 children are born with a detectable level of hearing loss in one or both ears. An early-stage researcher at ºÚÁϳԹÏÍø School of Medicine is receiving a major grant to help address the problem in an innovative way. Martin Basch,...