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Researchers Receive $6.5 Million NIH Grant to Use Big Data to Tackle Psoriasis
An experienced interdisciplinary team of psoriasis and computational researchers from ϳԹ School of Medicine (ϳԹ SOM) and University Hospitals Cleveland Medical Center (UHCMC) has received a $6.5M, 5-year grant from the National Institute of Arthritis, Musculoskeletal a...
Alex Huang, MD, PhD, Receives $450,000 from Pediatric Cancer Research Foundation
Alex Huang, MD, PhD Leading cancer researcher, Alex Huang MD, PhD, has received a $450,000 Basic Science grant from Pediatric Cancer Research Foundation to study targeted approaches for effectively eliminating metastatic osteosarcoma. “We’re very excited to study an important cancer that...
Researchers Borrow from AIDS Playbook to Tackle Rheumatic Heart Disease: Taking Services to the People
Emmy Okello, MBChB, PhD performs echocardiographic screening for rheumatic heart disease. Billions of US taxpayer dollars have been invested in Africa over the past 15 years to improve care for millions suffering from the HIV/AIDS epidemic; yet health systems on the continent continue to ...
Researchers Discover New Enzymes Central to Cell Function
Doctors have long treated heart attacks, improved asthma symptoms, and cured impotence by increasing levels of a single molecule in the body: nitric oxide. The tiny molecule can change how proteins function. But new research featured in Molecular Cellsuggests supplementing nitric oxide—NO—is only t...
Researchers Develop Highly Sensitive Swallowable Test to Detect Pre-cancerous Barrett's Esophagus
Investigators at ϳԹ School of Medicine and University Hospitals Cleveland Medical Center have developed a simple, swallowable test for early detection of Barrett’s esophagus that offers promise for preventing deaths from esophageal adenocarcinoma. Barrett’s esophagus (B...
New Antifungal Provides Hope in Fight Against Superbugs
Microscopic yeast have been wreaking havoc in hospitals around the world—creeping into catheters, ventilator tubes, and IV lines—and causing deadly invasive infection. One culprit species, Candida auris, is resistant to many antifungals, meaning once a person is infected, there are limited treatment...
Researchers Receive $2.8 Million to Repurpose FDA-approved Drugs to Treat Alzheimer’s Disease
Researchers from ϳԹ School of Medicine and collaborators have received a five-year, $2.8 million grant from the National Institute on Aging to identify FDA-approved medications that could be repurposed to treat Alzheimer’s disease. The award enables the researchers to de...
Zooming in on Protein to Prevent Kidney Stones
Researchers have applied Nobel prize-winning microscope technology to uncover an ion channel structure that could lead to new treatments for kidney stones. In a recent study published in Nature Structural and Molecular Biology, researchers revealed atomic-level details of the protein that serves as ...
Fish Use Deafness Gene to Sense Water Motion
Fish sense water motion the same way humans sense sound, according to new research out of ϳԹ School of Medicine. Researchers discovered a gene also found in humans helps zebrafish convert water motion into electrical impulses that are sent to the brain for perception. Th...
Selective Suppression of Inflammation Could Deplete HIV and Control HIV Activation
A class of anti-inflammatory drugs already FDA-approved for rheumatoid arthritis could “purge” the reservoir of infected immune cells in people infected by HIV, according to new research. When culturing cells from HIV-infected individuals, researchers found the medications tofacitinib and ruxolitin...