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ϳԹ Researchers to Examine the Role of Skin Prions in Fatal Neurodegenerative Human Prion Disease
Wenquan Zou, MD, PhD Affecting both people and animals, prion diseases are degenerative brain disorders that can debilitate or kill their victims. The most common form of prion disease affecting humans is sporadic Creutzfeldt-Jakob disease (sCJD). There are about 350 cases of the disease ...
Beyond Skin Deep: Understanding Disparities in Dermatology Services
The odds of a black or Hispanic patient visiting an outpatient dermatologist are about half that of a white patient with the same skin condition, according to a new study in JAMA Dermatology. Patients most likely to receive outpatient dermatologic services in the study were white, educated women. Th...
ϳԹ School of Medicine Receives NIH Funding to Investigate New Imaging Approach for Peripheral Vascular Disease
Sanjay Rajagopalan, MD ϳԹ School of Medicine has received a three-year, $1,118,556 grant from the National Heart, Lung, and Blood Institute of the National Institutes of Health to investigate a new imaging approach for diagnosing peripheral arterial disease, a...
ϳԹ’s Lan Zhou Receives $2M NIH Grant to Study Colorectal Cancer Development
Lan Zhou, MD, PhD Lan Zhou, MD, PhD, associate professor of pathology at ϳԹ School of Medicine, has received a five-year, $2 million grant from the National Cancer Institute of the National Institutes of Health to study human colorectal cancer. Her work focuse...
Researchers Stop Cell Suicide that Worsens Sepsis, Arthritis
Researchers from ϳԹ School of Medicine have discovered a way to stop immune cell death associated with multiple diseases, including sepsis, inflammatory bowel disease (IBD), and arthritis. The findings, published in Science Immunology, identify a chemical that potently ...
ϳԹ Receives Major Grant to Improve Food Systems in Cleveland Neighborhoods
Under the Tipping Points grant from the Foundation for Food and Agriculture Research (FFAR), a team led by Darcy Freedman, PhD, MPH, will conduct the Modeling the Future of Food in Your Neighborhood study that will examine several key food-system strategies. A multidisciplinary research t...
“Hike and Seek for Research” Event Benefits Pediatric Genetic Disorders
Take a hike! The second annual family- and dog-friendly Hike & Seek for Research will take place Sunday, September 9 at one of the award-winning Cleveland Metroparks, Brecksville Reservation. Guests can hike anytime between 10 a.m. and 5 p.m. Upon check-in at the Nature Center or Oak Grove Picnic...
A New Milestone in Laboratory Grown Human Brain Tissue
oligocortical spheroids A cutting-edge laboratory technique that turns human stem cells into brain-like tissue now recapitulates human brain development more accurately than ever, according to a new study from ϳԹ School of Medicine. The study, published in Nat...
Researchers Find Hidden Signals in RNAs that Regulate Protein Synthesis
Scientists have long known that RNA encodes instructions to make proteins. The building blocks that comprise RNA—A, U, C, and Gs—form a blueprint for the protein-making machinery in cells. To make proteins, the machinery latches on RNA at one end and then scans along the RNA until it reaches an AUG ...
Novel Therapy Delays Muscle Atrophy in Lou Gehrig’s Disease Model
Supplementing a single protein found in the spinal cord could help prevent symptoms of Lou Gehrig’s disease, according to a new study out of ϳԹ School of Medicine. Researchers found high levels of the protein—called mitofusion 2 or Mfn2—prevented nerve degeneration, musc...