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Preventing “Cell Wall Remodeling” May Hold Key to Defeating Intransigent Superbugs in Cystic Fibrosis, Other Diseases
B. multivorans is a notorious pathogen that can cause infections such as pneumonia in immune-compromised individuals with underlying lung diseases, including cystic fibrosis. This pathogen can also cause rapid clinical deterioration in patients, including blood stream infections, which can lead to d...
ϳԹ Researcher Awarded $1.3 Million to Develop Decision-Making Tool for Treating Intimate Partner Violence
ϳԹ School of Medicine’s Gunnur Karakurt, PhD has been awarded a four-year, $1.3 million grant from the National Institutes of Health to identify effective treatments for intimate partner violence (IPV), and to develop a decision-making tool for care providers. The projec...
Blood Cells Could Hold Master Clock Behind Aging
Blood cells could hold the key to aging, according to new research out of ϳԹ School of Medicine. In a study published in Aging Cell, researchers found human blood cells have an intrinsic clock that remains steady even after transplant. The researchers say the clock could...
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Researchers Develop New Approach for Vanquishing Superbugs
A scientific team from ϳԹ School of Medicine and Cleveland Clinic has developed a new way to identify second-line antibiotics that may be effective in killing germs already resistant to a first-line antibiotic – potentially helping overcome antibiotic resistance. This ne...
New Skin Test Detects Prion Infection Before Symptoms Appear
Microscopic examination of brain tissues of prion-infected animals. (Left) Staining shows spongiform degeneration. (Right) Staining shows intense misfolded prion protein. Prions can infect both humans and animals, causing Creutzfeldt-Jakob disease (CJD) in humans, mad cow disease in cattl...
ϳԹ’s John “Chip” Tilton, MD, Secures School of Medicine’s Fourth Falk Catalyst Award
John “Chip” Tilton, MD, of ϳԹ School of Medicine will receive $300,000 from the Dr. Ralph and Marian Falk Medical Research Trust to develop a virus-based “nanoPOD” (nanoscale PrOtein Delivery) platform to help treat rare genetic diseases. Tilton is associate professor an...
ϳԹ/UH Launch Bipolar CHOICE Trial Site
CLEVELAND - The Mood Disorders Program at ϳԹ School of Medicine and University Hospitals Case Medical Center, along with the Bipolar Trials Network, is launching Bipolar CHOICE (Clinical Health Outcomes Initiative in Comparative Effectiveness). The 10-site nationwide tri...
International TB Campaign Launches on World TB Day
CLEVELAND - Physicians across the globe are coming together to advocate for a large, underrepresented patient population – those suffering from tuberculosis (TB). On World TB Day, March 24th, a team of physician and researchers led by ϳԹ School of Medicine’s Tuberculosis...
Breakthrough Discovery Unveils “Master Switches” in Colon Cancer
CLEVELAND - A team of researchers at ϳԹ School of Medicine have identified a new mechanism by which colon cancer develops. By focusing on segments of DNA located between genes, or so-called “junk DNA,” the team has discovered a set of master switches, i.e., gene enhancer...
A toxic byproduct of hemoglobin could provide clues for possible treatments for cerebral hemorrhage and Creutzfeldt-Jakob Disease
Scientists at ϳԹ School of Medicine have identified a novel mechanism that could be used to protect the brain from damage due to stroke and a variety of neurodegenerative conditions, including sporadic Creutzfeldt-Jakob disease, Alzheimer’s disease, and Parkinson’s disea...