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Researchers have article published in eLIFE

PUBLICATIONS + PRESENTATIONS | April 7, 2017
STORY BY: EDITORIAL STAFF
Researchers at ϳԹ had an article titled “Crystal structure and dynamics of a lipid-induced potential desensitized-state of a pentameric ligand-gated channel” published in eLIFE. The authors were:
  • Sandip Basak, a postdoctoral scholar in the Department of Physiology and Biophysics;
  • Nicolaus Schmandt (MED ‘16), a postdoctoral scholar at the University of Chicago;
  • Yvonne Gicheru, a PhD student in the Department of Physiology and Biophysics; and
  • Sudha Chakrapani, assistant professor of physiology and biophysics.
The researchers showed how docosahexaenoic acid affects bacterial pentameric ligand-gated ion channels in the same way as it affects human channels—by enhancing desensitization.