Alberto Costa, professor of pediatrics at the School of Medicine, reviewed a study titled, “Intracellular chloride accumulation: a possible mechanism for cognitive deficits in Down syndrome” in the April issue of Nature Medicine.
The study, involving a mouse model of Down syndrome and analysis of human postmortem brain samples, found that a receptor signaling in Down syndrome may be excitatory. The finding is expected to lead to new clinical applications in Down syndrome.
of his "News and Views" article in the April issue of Nature Medicine.
